αE-catenin inhibits a Src–YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway

Cell–cell adhesion protein αE-catenin inhibits skin squamous cell carcinoma (SCC) development; however, the mechanisms responsible for this function are not completely understood. We report here that αE-catenin inhibits β4 integrin-mediated activation of SRC tyrosine kinase. SRC is the first discove...

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Vydáno v:Genes Dev
Hlavní autoři: Li, Peng, Silvis, Mark R., Honaker, Yuchi, Lien, Wen-Hui, Arron, Sarah T., Vasioukhin, Valeri
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826396/
https://ncbi.nlm.nih.gov/pubmed/27013234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.274951.115
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