Mutagenesis of some conserved residues in human 5-lipoxygenase: effects on enzyme activity.

Recombinant human 5-lipoxygenase (arachidonate:oxygen 5-oxidoreductase, EC 1.13.11.34) was expressed in Escherichia coli. In incubations of E. coli supernatants with arachidonic acid, 5-hydroxy-7,9,11,14-eicosatetraenoic acid and leukotriene A4 were formed, while incubation with 8,11,14-eicosatrieno...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Y Y, Rådmark, O, Samuelsson, B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1992
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC48263/
https://ncbi.nlm.nih.gov/pubmed/1731317
Etiketler: Etiketle
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