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DNA demethylation caused by 5-Aza-2′-deoxycytidine induces mitotic alterations and aneuploidy
Aneuploidy, the unbalanced number of chromosomes in a cell, is considered a prevalent form of genetic instability and is largely acknowledged as a condition implicated in tumorigenesis. Epigenetic alterations like DNA hypomethylation have been correlated with cancer initiation/progression. Furthermo...
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| Publicado no: | Oncotarget |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826165/ https://ncbi.nlm.nih.gov/pubmed/26771138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6897 |
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