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Induction of MAGE Genes in Lymphoid Cells by the Demethylating Agent 5‐Aza‐2′‐deoxycytidine

MAGE genes encoding tumor antigens recognized by cytotoxic T lymphocytes are appropriate target molecules for specific immunotherapy of cancer. We have investigated whether the demethylating agent 5‐aza‐2′‐deoxycytidine (DAC) induces MAGE‐1, ‐2, ‐3, and ‐6 in normal and malignant lymphoid cells. DAC...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Shichijo, Shigeki, Yamada, Akira, Sagawa, Kimitaka, Iwamoto, Osamu, Sakata, Motoko, Nagai, Kojiro, Itoh, Kyogo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921158/
https://ncbi.nlm.nih.gov/pubmed/8698626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb00288.x
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