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Induction of MAGE Genes in Lymphoid Cells by the Demethylating Agent 5‐Aza‐2′‐deoxycytidine

MAGE genes encoding tumor antigens recognized by cytotoxic T lymphocytes are appropriate target molecules for specific immunotherapy of cancer. We have investigated whether the demethylating agent 5‐aza‐2′‐deoxycytidine (DAC) induces MAGE‐1, ‐2, ‐3, and ‐6 in normal and malignant lymphoid cells. DAC...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Shichijo, Shigeki, Yamada, Akira, Sagawa, Kimitaka, Iwamoto, Osamu, Sakata, Motoko, Nagai, Kojiro, Itoh, Kyogo
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921158/
https://ncbi.nlm.nih.gov/pubmed/8698626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb00288.x
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