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Genome-wide demethylation by 5-aza-2′-deoxycytidine alters the cell fate of stem/progenitor cells
DNA methyltransferase (DNMT) inhibitor 5-aza-2′-deoxycytidine (5-aza-CdR) is able to cause DNA demethylation in the genome and induce the expression of silenced genes. Whether DNA demethylation can affect the gene expression of stem/progenitor cells has not been understood. Mouse utricle epithelia-d...
में बचाया:
| में प्रकाशित: | Stem Cell Rev |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320036/ https://ncbi.nlm.nih.gov/pubmed/25096638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-014-9542-z |
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