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RAS-MAPK in ALK targeted therapy resistance
The clinical success of ALK targeted therapy is limited by resistance. To identify rational co-targeting strategies to enhance clinical outcomes, we explored the molecular basis of ALK oncogene dependence in ALK gene rearrangement positive (ALK+) lung adenocarcinoma. We discovered that the RAS-RAF-M...
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Publicado no: | Cell Cycle |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825705/ https://ncbi.nlm.nih.gov/pubmed/26654768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1096103 |
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