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Mechanisms of resistance to EGFR targeted therapies

EGFR is a validated therapeutic target in many human cancers. EGFR targeted therapies are in widespread clinical use in patients with non-small cell lung cancer and other tumor types. Despite the clinical success of EGFR targeted therapy, resistance to treatment is a significant barrier to the optim...

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Bibliografiske detaljer
Main Authors: Hrustanovic, Gorjan, Lee, Bianca J., Bivona, Trever G.
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667869/
https://ncbi.nlm.nih.gov/pubmed/23358468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.23627
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