Differential Role of G Protein-Coupled Receptor Kinase 5 in Physiological Versus Pathological Cardiac Hypertrophy

RATIONALE: G protein-coupled receptor (GPCR) kinases (GRKs) are dynamic regulators of cellular signaling. GRK5 is highly expressed within myocardium and is up-regulated in heart failure (HF). Although GRK5 is a critical regulator of cardiac GPCR signaling, recent data has uncovered non-canonical act...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Traynham, Christopher J., Cannavo, Alessandro, Zhou, Yan, Vouga, Alexandre G., Woodall, Benjamin P., Hullmann, Jonathan, Ibetti, Jessica, Gold, Jessica I., Chuprun, J. Kurt, Gao, Erhe, Koch, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825669/
https://ncbi.nlm.nih.gov/pubmed/26515328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.306961
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