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Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells

OBJECTIVES: Polymerase delta interacting protein 2 (Poldip2) has previously been implicated in migration, proliferation and extracellular matrix (ECM) production in vascular smooth muscle cells. To better understand the role of Poldip2 in ECM regulation, we investigated the mechanism responsible for...

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Détails bibliographiques
Publié dans:J Mol Cell Cardiol
Auteurs principaux: Fujii, Masakazu, Amanso, Angélica, Abrahão, Thalita B., Lassègue, Bernard, Griendling, Kathy K.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825175/
https://ncbi.nlm.nih.gov/pubmed/26801741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.01.016
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