Oligonucleotide-Mediated Genome Editing Provides Precision and Function to Engineered Nucleases and Antibiotics in Plants

Here, we report a form of oligonucleotide-directed mutagenesis for precision genome editing in plants that uses single-stranded oligonucleotides (ssODNs) to precisely and efficiently generate genome edits at DNA strand lesions made by DNA double strand break reagents. Employing a transgene model in...

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Veröffentlicht in:Plant Physiol
Hauptverfasser: Sauer, Noel J., Narváez-Vásquez, Javier, Mozoruk, Jerry, Miller, Ryan B., Warburg, Zachary J., Woodward, Melody J., Mihiret, Yohannes A., Lincoln, Tracey A., Segami, Rosa E., Sanders, Steven L., Walker, Keith A., Beetham, Peter R., Schöpke, Christian R., Gocal, Greg F.W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Plant Biologists 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825113/
https://ncbi.nlm.nih.gov/pubmed/26864017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.15.01696
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