Regulation of Ligand and Shear Stress-induced Insulin-like Growth Factor 1 (IGF1) Signaling by the Integrin Pathway

Mechanical loading of the skeleton, as achieved during daily movement and exercise, preserves bone mass and stimulates bone formation, whereas skeletal unloading from prolonged immobilization leads to bone loss. A functional interplay between the insulin-like growth factor 1 receptor (IGF1R), a majo...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Tahimic, Candice G. T., Long, Roger K., Kubota, Takuo, Sun, Maggie Yige, Elalieh, Hashem, Fong, Chak, Menendez, Alicia T., Wang, Yongmei, Vilardaga, Jean-Pierre, Bikle, Daniel D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825016/
https://ncbi.nlm.nih.gov/pubmed/26865633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693598
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