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Anabolic effects of IGF-1 signaling on the skeleton
This review focuses on the anabolic effects of IGF-1 signaling on the skeleton, emphasizing the requirement for IGF-1 signaling in normal bone formation and remodeling. We first discuss the genomic context, splicing variants, and species conservation of the IGF-1 locus. The modulation of IGF-1 actio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563099/ https://ncbi.nlm.nih.gov/pubmed/23382729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2013.00006 |
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