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Skeletal unloading induced insulin-like growth factor-I (IGF-I) non-responsiveness is not shared by platelet-derived growth factor: the selective role of integrins in IGF-I signaling
Integrin receptors bind extracellular matrix proteins, and this link between the cell membrane and the surrounding matrix may translate skeletal loading to biologic activity in osteoprogenitor cells. The interaction between integrin and growth factor receptors allows for mechanically induced regulat...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222734/ https://ncbi.nlm.nih.gov/pubmed/21932337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.511 |
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