Insight into Structure-Function Relationships and Inhibition of the Fatty Acyl-AMP Ligase (FadD32) Orthologs from Mycobacteria

Mycolic acids are essential components of the mycobacterial cell envelope, and their biosynthetic pathway is one of the targets of first-line antituberculous drugs. This pathway contains a number of potential targets, including some that have been identified only recently and have yet to be explored...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Guillet, Valérie, Galandrin, Ségolène, Maveyraud, Laurent, Ladevèze, Simon, Mariaule, Vincent, Bon, Cécile, Eynard, Nathalie, Daffé, Mamadou, Marrakchi, Hedia, Mourey, Lionel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825004/
https://ncbi.nlm.nih.gov/pubmed/26900152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712612
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