How RNase R Degrades Structured RNA: ROLE OF THE HELICASE ACTIVITY AND THE S1 DOMAIN

RNase R, a ubiquitous 3′ exoribonuclease, plays an important role in many aspects of RNA metabolism. In contrast to other exoribonucleases, RNase R can efficiently degrade highly structured RNAs, but the mechanism by which this is accomplished has remained elusive. It is known that RNase R contains...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Hossain, Sk Tofajjen, Malhotra, Arun, Deutscher, Murray P.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824996/
https://ncbi.nlm.nih.gov/pubmed/26872969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.717991
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