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Insights Into How RNase R Degrades Structured RNA: Analysis of the Nuclease Domain
RNase R readily degrades highly structured RNA, whereas its paralogue, RNase II, is unable to do so. Furthermore, the nuclease domain of RNase R, devoid of all canonical RNA binding domains, is sufficient for this activity. RNase R also binds RNA more tightly within its catalytic channel than does R...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786168/ https://ncbi.nlm.nih.gov/pubmed/19361424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.01.068 |
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