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Helicase Activity Plays a Crucial Role for RNase R Function in Vivo and for RNA Metabolism
RNase R is a 3′ to 5′ hydrolytic exoribonuclease that has the unusual ability to digest highly structured RNA. The enzyme possesses an intrinsic, ATP-dependent RNA helicase activity that is essential in vitro for efficient nuclease activity against double-stranded RNA substrates, particularly at low...
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| Published in: | J Biol Chem |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850284/ https://ncbi.nlm.nih.gov/pubmed/27022019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C116.726091 |
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