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Helicase Activity Plays a Crucial Role for RNase R Function in Vivo and for RNA Metabolism

RNase R is a 3′ to 5′ hydrolytic exoribonuclease that has the unusual ability to digest highly structured RNA. The enzyme possesses an intrinsic, ATP-dependent RNA helicase activity that is essential in vitro for efficient nuclease activity against double-stranded RNA substrates, particularly at low...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hossain, Sk Tofajjen, Deutscher, Murray P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850284/
https://ncbi.nlm.nih.gov/pubmed/27022019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C116.726091
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