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The Helicase Activity of Ribonuclease R Is Essential for Efficient Nuclease Activity

RNase R, which belongs to the RNB family of enzymes, is a 3′ to 5′ hydrolytic exoribonuclease able to digest highly structured RNA. It was previously reported that RNase R possesses an intrinsic helicase activity that is independent of its ribonuclease activity. However, the properties of this helic...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Hossain, Sk Tofajjen, Malhotra, Arun, Deutscher, Murray P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505480/
https://ncbi.nlm.nih.gov/pubmed/25931119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.650176
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