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Transfer-messenger RNA-SmpB Protein Regulates Ribonuclease R Turnover by Promoting Binding of HslUV and Lon Proteases

RNase R, an important exoribonuclease involved in degradation of structured RNA, is subject to a novel mechanism of regulation. The enzyme is extremely unstable in rapidly growing cells but becomes stabilized under conditions of stress, such as stationary phase or cold shock. RNase R instability res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liang, Wenxing, Deutscher, Murray P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460448/
https://ncbi.nlm.nih.gov/pubmed/22879590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.375287
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