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Disease relevance of phosphorylated ubiquitin (p-S65-Ub)

Here, we present a summary of our recent findings on the (patho-)physiological relevance of PINK1-phosphorylated ubiquitin (p-S65-Ub). Using novel polyclonal antibodies, we find that p-S65-Ub specifically accumulates on damaged mitochondria. Phosphorylation of ubiquitin on serine 65 depends on the a...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Fiesel, Fabienne C, Springer, Wolfdieter
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824591/
https://ncbi.nlm.nih.gov/pubmed/26389970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1091912
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