Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux

Metastatic renal cell carcinomas (mRCC) are highly vascularized tumors that are a paradigm for the treatment with antiangiogenesis drugs targeting the vascular endothelial growth factor (VEGF) pathway. The available drugs increase the time to progression but are not curative and the patients eventua...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Autophagy
Asıl Yazarlar: Giuliano, Sandy, Cormerais, Yann, Dufies, Maeva, Grépin, Renaud, Colosetti, Pascal, Belaid, Amine, Parola, Julien, Martin, Anthony, Lacas-Gervais, Sandra, Mazure, Nathalie M, Benhida, Rachid, Auberger, Patrick, Mograbi, Baharia, Pagès, Gilles
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Translational Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824581/
https://ncbi.nlm.nih.gov/pubmed/26312386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1085742
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller