VEGFC acts as a double-edged sword in renal cell carcinoma aggressiveness

Hypoxic zones are common features of metastatic tumors. Due to inactivation of the von Hippel-Lindau gene (VHL), renal cell carcinomas (RCC) show constitutive stabilization of the alpha subunit of the hypoxia-inducible factor (HIF). Thus, RCC represents a model of chronic hypoxia. Development of the...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Ndiaye, Papa Diogop, Dufies, Maeva, Giuliano, Sandy, Douguet, Laetitia, Grépin, Renaud, Durivault, Jérôme, Lenormand, Philippe, Glisse, Natacha, Mintcheva, Janita, Vouret-Craviari, Valérie, Mograbi, Baharia, Wurmser, Maud, Ambrosetti, Damien, Rioux-Leclercq, Nathalie, Maire, Pascal, Pagès, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376471/
https://ncbi.nlm.nih.gov/pubmed/30809300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.27794
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