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Crystal Structure-Guided Design of Self-assembling RNA Nanotriangles

RNA nanotechnology harnesses RNA structural motifs to build nano-sized architectures which assemble through selective base pair interactions. Here, we report the crystal structure-guided design of highly stable RNA nanotriangles that self-assemble cooperatively from short oligonucleotides. The cryst...

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Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Boerneke, Mark A., Dibrov, Sergey M., Hermann, Thomas
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824544/
https://ncbi.nlm.nih.gov/pubmed/26914842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201600233
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