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Crystal structure of a benzimidazole hepatitis C virus inhibitor free and in complex with the viral RNA target
The crystal structure of 8-((dimethylamino)methyl)-1-(3-(dimethylamino)propyl)-1,7,8,9-tetrahydrochromeno[5,6-d]imidazol-2-amine (1), an inhibitor of the hepatitis C virus internal ribosome entry site, is described and compared to the structure of the compound in complex with the viral RNA target. C...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673731/ https://ncbi.nlm.nih.gov/pubmed/23750099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10870-013-0410-5 |
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