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A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer

Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that is overexpressed in many types of tumors, including pancreatic cancer, and plays an important role in cell adhesion and survival signaling. Pancreatic cancer is a lethal disease and is very resistant to chemotherapy, and FAK has been...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Hochwald, Steven N., Nyberg, Carl, Zheng, Min, Zheng, Donghang, Wood, Cheng, Massoll, Nicole A., Magis, Andrew, Ostrov, David, Cance, William G., Golubovskaya, Vita M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824314/
https://ncbi.nlm.nih.gov/pubmed/19571674
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