A small molecule inhibitor 1,2,4,5-Benzenetetraamine tetrahydrochloride, targeting the Y397 site of Focal Adhesion Kinase decreases tumor growth

Lignende værker

• Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth
  af: Golubovskaya, Vita M, et al.
  Udgivet: (2013)
• Inhibition of Focal Adhesion Kinase Decreases Tumor Growth in Human Neuroblastoma
  af: Beierle, Elizabeth A., et al.
  Udgivet: (2010)
• Neurofibromin physically interacts with the N-terminal domain of Focal Adhesion Kinase
  af: Kweh, Frederick, et al.
  Udgivet: (2009)
• A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl) -3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo
  af: Golubovskaya, Vita M., et al.
  Udgivet: (2012)
• A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer
  af: Hochwald, Steven N., et al.
  Udgivet: (2009)