Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma

Bromodomain and extra terminal domain (BET) proteins are important epigenetic regulators facilitating the transcription of genes in chromatin areas linked to acetylated histones. JQ1, a BET protein inhibitor, has antiproliferative activity against many cancers, mainly through inhibition of c-MYC and...

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Detaylı Bibliyografya
Yayımlandı:Int J Cancer
Asıl Yazarlar: Lee, Dhong Hyun, Qi, Jun, Bradner, James E., Said, Jonathan W., Doan, Ngan B., Forscher, Charles, Yang, Henry, Koeffler, H. Phillip
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824295/
https://ncbi.nlm.nih.gov/pubmed/25307878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29269
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