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Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma
Bromodomain and extra terminal domain (BET) proteins are important epigenetic regulators facilitating the transcription of genes in chromatin areas linked to acetylated histones. JQ1, a BET protein inhibitor, has antiproliferative activity against many cancers, mainly through inhibition of c-MYC and...
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| Publicado no: | Int J Cancer |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824295/ https://ncbi.nlm.nih.gov/pubmed/25307878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29269 |
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