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Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets

BACKGROUND: Liposarcoma, the most common soft tissue tumor, is understudied cancer, and limited progress has been made in the treatment of metastatic disease. The Achilles heel of cancer often is their kinases that are excellent therapeutic targets. However, very limited knowledge exists of therapeu...

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發表在:J Hematol Oncol
Main Authors: Kanojia, Deepika, Garg, Manoj, Martinez, Jacqueline, M.T., Anand, Luty, Samuel B., Doan, Ngan B., Said, Jonathan W., Forscher, Charles, Tyner, Jeffrey W., Koeffler, H. Phillip
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683536/
https://ncbi.nlm.nih.gov/pubmed/29132397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0540-x
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