Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets

BACKGROUND: Liposarcoma, the most common soft tissue tumor, is understudied cancer, and limited progress has been made in the treatment of metastatic disease. The Achilles heel of cancer often is their kinases that are excellent therapeutic targets. However, very limited knowledge exists of therapeu...

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Publicado en:J Hematol Oncol
Autores principales: Kanojia, Deepika, Garg, Manoj, Martinez, Jacqueline, M.T., Anand, Luty, Samuel B., Doan, Ngan B., Said, Jonathan W., Forscher, Charles, Tyner, Jeffrey W., Koeffler, H. Phillip
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683536/
https://ncbi.nlm.nih.gov/pubmed/29132397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0540-x
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