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Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma
We investigated the use of cucurbitacin B, a plant-derived tetracyclic triterpenoid, as a single agent or in combination with methotrexate (MTX) for human osteosarcoma (OS) treatment. Cucurbitacin B showed antiproliferative activity against seven human OS cell lines in vitro accompanying G2/M cell c...
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| Publicado no: | Cancer Lett |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4925102/ https://ncbi.nlm.nih.gov/pubmed/21440986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.03.001 |
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