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Induction of p53-independent apoptosis by ectopic expression of HOXA5 in human liposarcomas

Dedifferentiated liposarcoma (DDLPS) is a highly malignant subtype of human liposarcoma (LPS), whose genomic profile is characterized by chromosomal amplification at 12q13-q22. miR-26a-2 is one of the most frequently amplified genes in the region, and inhibition of its downstream target genes likely...

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Publicat a:Sci Rep
Autors principals: Lee, Dhong Hyun, Forscher, Charles, Vizio, Dolores Di, Koeffler, H. Phillip
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518222/
https://ncbi.nlm.nih.gov/pubmed/26219418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12580
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