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Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis
The p53 protein activates cellular death programs through multiple pathways. Because the high frequency of p53 mutations in human tumors is believed to contribute to resistance to commonly used chemotherapeutic agents, it is important to identify drugs that induce p53-independent cell death and to d...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC544072/ https://ncbi.nlm.nih.gov/pubmed/15618392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408592102 |
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