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Synthesis and In Vitro Efficacy of MMP9-activated NanoDendrons

Chemotherapeutics such as doxorubicin (DOX) and paclitaxel (PXL) have dose limiting systemic toxicities including cardiotoxicity and peripheral neuropathy. Delivery strategies to minimize these undesirable effects are needed and could improve efficacy, while reducing patient morbidity. Here DOX and...

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Bibliografische gegevens
Gepubliceerd in:Mol Pharm
Hoofdauteurs: Samuelson, Lynn E., Scherer, Randy L., Matrisian, Lynn M., McIntyre, J. Oliver, Bornhop, Darryl J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824186/
https://ncbi.nlm.nih.gov/pubmed/23750801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4002206
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