New Tools for the Quantitative Assessment of Prodrug Delivery and Neurotoxicity

Systemic off-target toxicities, including neurotoxicity, are prevalent side effects in cancer patients treated with a number of otherwise highly efficacious anticancer drugs. In the current study, we have: 1) developed a new analytical metric for the in vivo preclinical assessment of systemic toxici...

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Detalhes bibliográficos
Publicado no:Neurotoxicology
Main Authors: Samuelson, Lynn E., Scherer, Randy L., VanSaun, Michael N., Fan, Kang-Hsien, Dozier, E. Ashley, Carter, Kathy J., Koyama, Tatsuki, Shyr, Yu, Aschner, Michael, Stanwood, Gregg D., Bornhop, Darryl J., Matrisian, Lynn M., McIntyre, J. Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501381/
https://ncbi.nlm.nih.gov/pubmed/25732874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2015.02.005
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