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Synthesis and In Vitro Efficacy of MMP9-activated NanoDendrons

Chemotherapeutics such as doxorubicin (DOX) and paclitaxel (PXL) have dose limiting systemic toxicities including cardiotoxicity and peripheral neuropathy. Delivery strategies to minimize these undesirable effects are needed and could improve efficacy, while reducing patient morbidity. Here DOX and...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Samuelson, Lynn E., Scherer, Randy L., Matrisian, Lynn M., McIntyre, J. Oliver, Bornhop, Darryl J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824186/
https://ncbi.nlm.nih.gov/pubmed/23750801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4002206
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