Analysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elements

A mechanism by which control DNA elements regulate transcription over large linear genomic distances is by achieving close physical proximity with genes, and looping of the intervening chromatin paths. Alterations of such regulatory ‘chromatin looping’ systems are likely to play a critical role in h...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Moisan, Stéphanie, Berlivet, Soizik, Ka, Chandran, Gac, Gérald Le, Dostie, Josée, Férec, Claude
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824072/
https://ncbi.nlm.nih.gov/pubmed/26615198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1300
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