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Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene

Identification of regulatory elements and their target genes is complicated by the fact that regulatory elements can act over large genomic distances. Identification of long-range acting elements is particularly important in the case of disease genes as mutations in these elements can result in huma...

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Detalhes bibliográficos
Main Authors: Gheldof, Nele, Smith, Emily M., Tabuchi, Tomoko M., Koch, Christoph M., Dunham, Ian, Stamatoyannopoulos, John A., Dekker, Job
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910055/
https://ncbi.nlm.nih.gov/pubmed/20360044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq175
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