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Inhibition of glycogen synthase kinase 3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptor α

Our previous studies have demonstrated that inhibition of glycogen synthase kinase 3β (GSK3β) activity protects mice from acute liver failure (ALF), whereas its protective and regulatory mechanism remains elusive. Autophagy is a recently recognized rudimentary cellular response to inflammation and i...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Ren, F, Zhang, L, Zhang, X, Shi, H, Wen, T, Bai, L, Zheng, S, Chen, Y, Chen, D, Li, L, Duan, Z
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823957/
https://ncbi.nlm.nih.gov/pubmed/27010852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.56
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