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Glycogen synthase kinase 3α regulates urine concentrating mechanism in mice

In mammals, glycogen synthase kinase (GSK)3 comprises GSK3α and GSK3β isoforms. GSK3β has been shown to play a role in the ability of kidneys to concentrate urine by regulating vasopressin-mediated water permeability of collecting ducts, whereas the role of GSK3α has yet to be discerned. To investig...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Nørregaard, Rikke, Tao, Shixin, Nilsson, Line, Woodgett, James R., Kakade, Vijayakumar, Yu, Alan S. L., Howard, Christiana, Rao, Reena
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360031/
https://ncbi.nlm.nih.gov/pubmed/25608967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00516.2014
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