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Glycogen synthase kinase-3β promotes cyst expansion in polycystic kidney disease

Polycystic kidney diseases (PKDs) are inherited disorders characterized by the formation of fluid filled renal cysts. Elevated cAMP levels in PKDs stimulate progressive cyst enlargement involving cell proliferation and transepithelial fluid secretion often leading to end stage renal disease. The gly...

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Bibliografski detalji
Izdano u:Kidney Int
Glavni autori: Tao, Shixin, Kakade, Vijayakumar, Woodgett, James, Pandey, Pankaj, Suderman, Erin, Rajagopal, Madhumitha, Rao, Reena
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449797/
https://ncbi.nlm.nih.gov/pubmed/25629553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.427
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