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Glycogen synthase kinase-3β promotes cyst expansion in polycystic kidney disease

Polycystic kidney diseases (PKDs) are inherited disorders characterized by the formation of fluid filled renal cysts. Elevated cAMP levels in PKDs stimulate progressive cyst enlargement involving cell proliferation and transepithelial fluid secretion often leading to end stage renal disease. The gly...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Tao, Shixin, Kakade, Vijayakumar, Woodgett, James, Pandey, Pankaj, Suderman, Erin, Rajagopal, Madhumitha, Rao, Reena
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449797/
https://ncbi.nlm.nih.gov/pubmed/25629553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.427
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