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A cAMP and CREB-mediated feed-forward mechanism regulates GSK3β in polycystic kidney disease

Glycogen synthase kinase 3β (GSK3β), a serine/threonine protein kinase, is commonly known to be regulated at the level of its activity. However, in some diseases including polycystic kidney disease (PKD), GSK3β expression is increased and plays a pathophysiological role. The current studies aimed to...

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Bibliografske podrobnosti
izdano v:J Mol Cell Biol
Main Authors: Kakade, Vijayakumar R., Tao, Shixin, Rajagopal, Madhumitha, Zhou, Xia, Li, Xiaogang, Yu, Alan S.L., Calvet, James P., Pandey, Pankaj, Rao, Reena
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181316/
https://ncbi.nlm.nih.gov/pubmed/27190311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjw022
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