Inhibition of glycogen synthase kinase 3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptor α

Our previous studies have demonstrated that inhibition of glycogen synthase kinase 3β (GSK3β) activity protects mice from acute liver failure (ALF), whereas its protective and regulatory mechanism remains elusive. Autophagy is a recently recognized rudimentary cellular response to inflammation and i...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Ren, F, Zhang, L, Zhang, X, Shi, H, Wen, T, Bai, L, Zheng, S, Chen, Y, Chen, D, Li, L, Duan, Z
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823957/
https://ncbi.nlm.nih.gov/pubmed/27010852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.56
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