Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α

Non-alcoholic fatty liver disease is the most rapidly growing form of liver disease and if left untreated can result in non-alcoholic steatohepatitis, ultimately resulting in liver cirrhosis and failure. Biliverdin reductase A (BVRA) is a multifunctioning protein primarily responsible for the reduct...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Hinds, Terry D., Burns, Katherine A., Hosick, Peter A., McBeth, Lucien, Nestor-Kalinoski, Andrea, Drummond, Heather A., AlAmodi, Abdulhadi A., Hankins, Michael W., Vanden Heuvel, John P., Stec, David E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122784/
https://ncbi.nlm.nih.gov/pubmed/27738106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.731703
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