PML-RAR alpha induces the downmodulation of HHEX: a key event responsible for the induction of an angiogenetic response

BACKGROUND: Recent studies indicate that angiogenesis is important in the pathogenesis of acute myeloid leukemias (AMLs). Among the various AMLs, the bone marrow angiogenetic response is particularly pronounced in acute promyelocytic leukemia (APL). However, the molecular mechanisms responsible for...

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Bibliografske podrobnosti
izdano v:J Hematol Oncol
Main Authors: Saulle, Ernestina, Petronelli, Alessia, Pelosi, Elvira, Coppotelli, Elena, Pasquini, Luca, Ilari, Ramona, Lo-Coco, Francesco, Testa, Ugo
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823896/
https://ncbi.nlm.nih.gov/pubmed/27052408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0262-5
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