PML-RAR alpha induces the downmodulation of HHEX: a key event responsible for the induction of an angiogenetic response

BACKGROUND: Recent studies indicate that angiogenesis is important in the pathogenesis of acute myeloid leukemias (AMLs). Among the various AMLs, the bone marrow angiogenetic response is particularly pronounced in acute promyelocytic leukemia (APL). However, the molecular mechanisms responsible for...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Hematol Oncol
Prif Awduron: Saulle, Ernestina, Petronelli, Alessia, Pelosi, Elvira, Coppotelli, Elena, Pasquini, Luca, Ilari, Ramona, Lo-Coco, Francesco, Testa, Ugo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823896/
https://ncbi.nlm.nih.gov/pubmed/27052408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0262-5
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