PML-RAR alpha induces the downmodulation of HHEX: a key event responsible for the induction of an angiogenetic response

BACKGROUND: Recent studies indicate that angiogenesis is important in the pathogenesis of acute myeloid leukemias (AMLs). Among the various AMLs, the bone marrow angiogenetic response is particularly pronounced in acute promyelocytic leukemia (APL). However, the molecular mechanisms responsible for...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Saulle, Ernestina, Petronelli, Alessia, Pelosi, Elvira, Coppotelli, Elena, Pasquini, Luca, Ilari, Ramona, Lo-Coco, Francesco, Testa, Ugo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823896/
https://ncbi.nlm.nih.gov/pubmed/27052408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0262-5
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