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PML-RAR alpha induces the downmodulation of HHEX: a key event responsible for the induction of an angiogenetic response

BACKGROUND: Recent studies indicate that angiogenesis is important in the pathogenesis of acute myeloid leukemias (AMLs). Among the various AMLs, the bone marrow angiogenetic response is particularly pronounced in acute promyelocytic leukemia (APL). However, the molecular mechanisms responsible for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Hematol Oncol
Hauptverfasser: Saulle, Ernestina, Petronelli, Alessia, Pelosi, Elvira, Coppotelli, Elena, Pasquini, Luca, Ilari, Ramona, Lo-Coco, Francesco, Testa, Ugo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823896/
https://ncbi.nlm.nih.gov/pubmed/27052408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0262-5
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