Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer

Somatic mutations found within the tyrosine kinase domain (TKD) of the human epidermal growth factor (HER) family of receptors have been implicated in the development and progression of non-small cell lung cancer (NSCLC). However, no conclusive reports have described pathogenic mutations in kinase-i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Umelo, Ijeoma, Noeparast, Amir, Chen, Gang, Renard, Marleen, Geers, Caroline, Vansteenkiste, Johan, Giron, Philippe, De Wever, Olivier, Teugels, Erik, De Grève, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823091/
https://ncbi.nlm.nih.gov/pubmed/26689995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6585
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