Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer

Somatic mutations found within the tyrosine kinase domain (TKD) of the human epidermal growth factor (HER) family of receptors have been implicated in the development and progression of non-small cell lung cancer (NSCLC). However, no conclusive reports have described pathogenic mutations in kinase-i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Umelo, Ijeoma, Noeparast, Amir, Chen, Gang, Renard, Marleen, Geers, Caroline, Vansteenkiste, Johan, Giron, Philippe, De Wever, Olivier, Teugels, Erik, De Grève, Jacques
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2015
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823091/
https://ncbi.nlm.nih.gov/pubmed/26689995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6585
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