Oncogenic KRAS activates an embryonic stem cell-like program in human colon cancer initiation

Colorectal cancer is the third most frequently diagnosed cancer worldwide. Prevention of colorectal cancer initiation represents the most effective overall strategy to reduce its associated morbidity and mortality. Activating KRAS mutation (KRAS(mut)) is the most prevalent oncogenic driver in colore...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Le Rolle, Anne-France, Chiu, Thang K., Zeng, Zhaoshi, Shia, Jinru, Weiser, Martin R., Paty, Philip B., Chiu, Vi K.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823026/
https://ncbi.nlm.nih.gov/pubmed/26744320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6818
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