The prognostic significance of CXCL1 hypersecretion by human colorectal cancer epithelia and myofibroblasts

BACKGROUND: Clinical therapy for metastatic colorectal cancer (CRC) remains limited, especially when the tumor harbors a KRAS mutation. This study aimed to identify prognostic biomarkers in CRC that are accessible for therapeutic inhibition. METHODS: Conditioned media from human CRC epithelial cells...

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Dades bibliogràfiques
Publicat a:J Transl Med
Autors principals: le Rolle, Anne-France, Chiu, Thang K, Fara, Michael, Shia, Jinru, Zeng, Zhaoshi, Weiser, Martin R, Paty, Philip B, Chiu, Vi K
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477596/
https://ncbi.nlm.nih.gov/pubmed/26104296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0555-4
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