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α-Arylation of Saturated Azacycles and N-Methylamines via Palladium(II)-catalyzed C(sp(3))–H Coupling
Pd(II)-catalyzed α-C(sp(3))–H arylation of pyrrolidines, piperidines, azepanes and N-methyl amines with arylboronic acids has been developed for the first time. This transformation is applicable to both a wide array of pyrrolidines and boronic acids, including heteroaromatic boronic acids. A diaster...
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| Publicado en: | J Am Chem Soc |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4822695/ https://ncbi.nlm.nih.gov/pubmed/26322957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b06740 |
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